HIST2H2AC Antibody

Product Specifications

Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family.

NCBI Gene ID

8338

Swiss Prot

Q16777

Accession Number

Q16777

Host

Rabbit

Reactivity

Human

Immunogen

This HIST2H2AC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids from the Central region of human HIST2H2AC.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat, Bovine, Xenopus, Mouse, Chicken, Monkey, Zebrafish, D

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

14 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

HIST2H2AC

NCBI Official Name

Histone H2A type 2-C

NCBI Organism

Homo sapiens

Background Reference 01

Ishibashi, T., et al. Biochemistry 48 (22) :5007-5017 (2009)

Background Reference 02

Karaczyn, A.A., et al. Ann. Clin. Lab. Sci. 39 (3) :251-262 (2009)

Background Reference 03

Pinato, S., et al. BMC Mol. Biol. 10, 55 (2009) :

Background Reference 04

Guerrero-Santoro, J., et al. Cancer Res. 68 (13) :5014-5022 (2008)

Other Product Names

Histone H2A type 2-C, Histone H2A-GL101, Histone H2A/q, HIST2H2AC, H2AFQ

Tested Applications

Protein ID

47117890

Physical Properties

Liquid

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