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NR2E1 Antibody

Product Specifications

Background

Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity. May be required for brain development. May be involved in the regulation of retinal development (By similarity) .

NCBI Gene ID

7101

Swiss Prot

Q9Y466

Accession Number

Q9Y466

Host

Rabbit

Reactivity

Human

Immunogen

This NR2E1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-102 amino acids from the Central region of human NR2E1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Chicken, Mouse, Xenopus

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

43 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

NR2E1

NCBI Official Name

Nuclear receptor subfamily 2 group E member 1

NCBI Organism

Homo sapiens

Background Reference 01

Liu, H.K., et al. Genes Dev. 24 (7) :683-695 (2010)

Background Reference 02

Iwahara, N., et al. Biochem. Biophys. Res. Commun. 386 (4) :671-675 (2009)

Background Reference 03

De Krom, M., et al. Biol. Psychiatry 65 (7) :625-630 (2009)

Background Reference 04

Kumar, R.A., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 147B (6), 880-889 (2008) :

Other Product Names

Nuclear receptor subfamily 2 group E member 1, Nuclear receptor TLX, Protein tailless homolog, Tll, hTll, NR2E1, TLX

Tested Applications

WB

Protein ID

9910804

Physical Properties

Liquid

Curated Selection

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