ST6GAL1 Antibody

Product Specifications

Background

This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Three transcript variants encoding two different isoforms have been described.

NCBI Gene ID

6480

Swiss Prot

P15907

Accession Number

P15907

Host

Rabbit

Reactivity

Human

Immunogen

This ST6GAL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-206 amino acids from the Central region of human ST6GAL1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

47 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ST6GAL1

NCBI Official Name

Beta-galactoside alpha-2,6-sialyltransferase 1

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 02

Mondal, S., et al. Leuk. Res. 34 (4) :463-470 (2010)

Background Reference 03

Lee, M., et al. Oncol. Rep. 23 (3) :757-761 (2010)

Background Reference 04

Daly, A.K., et al. Nat. Genet. 41 (7) :816-819 (2009)

Other Product Names

Beta-galactoside alpha-2,6-sialyltransferase 1, Alpha 2,6-ST 1, B-cell antigen CD75, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1, ST6Gal I, ST6GalI, Sialyltransferase 1, ST6GAL1, SIAT1