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MMP26 Antibody

Product Specifications

Background

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The encoded protein degrades type IV collagen, fibronectin, fibrinogen, casein, vitronectin, alpha 1-antitrypsin, alpha 2-macroglobulin, and insulin-like growth factor-binding protein 1, and activates MMP9 by cleavage. The protein differs from most MMP family members in that it lacks a conserved C-terminal protein domain.

NCBI Gene ID

56547

Swiss Prot

Q9NRE1

Accession Number

Q9NRE1

Host

Rabbit

Reactivity

Human

Immunogen

This MMP26 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-125 amino acids from the Central region of human MMP26.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=60-765

Calculated Molecular Weight

30 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

MMP26

NCBI Official Name

Matrix metalloproteinase-26

NCBI Organism

Homo sapiens

Background Reference 01

De Amorim, R.F., et al. Acta Odontol. Scand. 68 (4) :228-231 (2010)

Background Reference 02

Ban, J.Y., et al. Life Sci. 86 (19-20), 756-759 (2010) :

Background Reference 03

Deng, Y., et al. Oncol. Rep. 23 (1) :69-78 (2010)

Background Reference 04

Johnatty, S.E., et al. PLoS Genet. (7), E1001016 (2010) :

Other Product Names

Matrix metalloproteinase-26, MMP-26, 3424-, Endometase, Matrilysin-2, MMP26

Tested Applications

WB

Protein ID

13629493

Physical Properties

Liquid

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