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NFE2L3 Antibody

Product Specifications

Background

This gene encodes a member of the cap 'n' collar basic-region leucine zipper family of transcription factors. The encoded protein heterodimerizes with small musculoaponeurotic fibrosarcoma factors to bind antioxidant response elements in target genes. This protein is a membrane bound glycoprotein that is targeted to the endoplasmic reticulum and the nuclear envelope. Pseudogenes of this gene are found on chromosomes 16, 17, and 18.

NCBI Gene ID

9603

Swiss Prot

Q9Y4A8

Accession Number

Q9Y4A8

Host

Rabbit

Reactivity

Human

Immunogen

This NFE2L3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 666-694 amino acids from the C-terminal region of human NFE2L3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

76 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

NFE2L3

NCBI Official Name

Nuclear factor erythroid 2-related factor 3

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 02

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 03

Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)

Background Reference 04

Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

Other Product Names

Nuclear factor erythroid 2-related factor 3, NF-E2-related factor 3, NFE2-related factor 3, Nuclear factor, erythroid derived 2, like 3, NFE2L3, NRF3

Tested Applications

WB

Protein ID

56404677

Physical Properties

Liquid

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