HBE1 Antibody

Product Specifications

Background

The epsilon globin gene (HBE) is normally expressed in the embryonic yolk sac: two epsilon chains together with two zeta chains (an alpha-like globin) constitute the embryonic hemoglobin Hb Gower I; two epsilon chains together with two alpha chains form the embryonic Hb Gower II. Both of these embryonic hemoglobins are normally supplanted by fetal, and later, adult hemoglobin. The five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon - G-gamma - A-gamma - delta - beta-3'

NCBI Gene ID

3046

Swiss Prot

P02100

Accession Number

P02100

Host

Rabbit

Reactivity

Human

Immunogen

This HBE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-83 amino acids from the Central region of human HBE1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rb

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

16 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:8000

Symbol

HBE1

NCBI Official Name

Hemoglobin subunit epsilon

NCBI Organism

Homo sapiens

Background Reference 01

Nuinoon, M., et al. Hum. Genet. (2009) In press :

Background Reference 02

Tachavanich, K., et al. Southeast Asian J. Trop. Med. Public Health 40 (2) :306-316 (2009)

Background Reference 03

Naka, I., et al. Biochem. Genet. 46 (11-12), 708-711 (2008) :

Background Reference 04

Winichagoon, P., et al. Transl Res 152 (4) :178-184 (2008)

Other Product Names

Hemoglobin subunit epsilon, Epsilon-globin, Hemoglobin epsilon chain, HBE1, HBE

Tested Applications

Protein ID

122726

Physical Properties

Liquid

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