GGT1 Antibody

Product Specifications

Background

The enzyme encoded by this gene catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. The enzyme is composed of a heavy chain and a light chain, which are derived from a single precursor protein, and is present in tissues involved in absorption and secretion. This enzyme is a member of the gamma-glutamyltransferase protein family, of which many members have not yet been fully characterized and some of which may represent pseudogenes. This gene is classified as type I gamma-glutamyltransferase. Multiple alternatively spliced variants, encoding the same protein, have been identified.

NCBI Gene ID

2678

Swiss Prot

P19440

Accession Number

P19440

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This GGT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 124-152 amino acids from the N-terminal region of human GGT1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Pig, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

61 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

GGT1

NCBI Official Name

Gamma-glutamyltranspeptidase 1

NCBI Organism

Homo sapiens

Background Reference 01

Speliotes, E.K., et al. Hepatology 52 (3) :904-912 (2010)

Background Reference 02

Ikeda, M., et al. Scand. J. Clin. Lab. Invest. 70 (3) :171-179 (2010)

Background Reference 03

Fujita, M., et al. Exp. Biol. Med. (Maywood) 235 (3) :335-341 (2010)

Background Reference 04

Kamatani, Y., et al. Nat. Genet. 42 (3) :210-215 (2010)

Other Product Names

Gamma-glutamyltranspeptidase 1, GGT 1, Gamma-glutamyltransferase 1, Glutathione hydrolase 1, Leukotriene-C4 hydrolase, CD224, Gamma-glutamyltranspeptidase 1 heavy chain, Gamma-glutamyltranspeptidase 1 light chain, GGT1, GGT