ZFP36L1 Antibody

Product Specifications

Background

This gene is a member of the TIS11 family of early response genes. Family members are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. The gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors.

NCBI Gene ID

677

Swiss Prot

Q07352

Accession Number

Q07352

Host

Rabbit

Reactivity

Mouse

Immunogen

This ZFP36L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-93 amino acids from the N-terminal region of human ZFP36L1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

36 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ZFP36L1

NCBI Official Name

Zinc finger protein 36, C3H1 type-like 1

NCBI Organism

Homo sapiens

Background Reference 01

Hacker, C., et al. Growth Factors 28 (3) :178-190 (2010)

Background Reference 02

Dubois, P.C., et al. Nat. Genet. 42 (4) :295-302 (2010)

Background Reference 03

Sinha, S., et al. J. Biol. Chem. 284 (47) :32610-32618 (2009)

Background Reference 04

Cheng, Z., et al. Genes Dev. 23 (9) :1106-1118 (2009)

Other Product Names

Zinc finger protein 36, C3H1 type-like 1, Butyrate response factor 1, EGF-response factor 1, ERF-1, Protein TIS11B, ZFP36L1, BERG36, BRF1, ERF1, RNF162B, TIS11B