SUB1 Antibody

Product Specifications

Background

General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA) .

NCBI Gene ID

10923

Swiss Prot

P53999

Accession Number

P53999

Host

Rabbit

Reactivity

Human

Immunogen

This SUB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-47 amino acids from the Central region of human SUB1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Monkey

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

14 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SUB1

NCBI Official Name

Activated RNA polymerase II transcriptional coactivator p15

NCBI Organism

Homo sapiens

Background Reference 01

Das, C., et al. J. Mol. Biol. 397 (1) :1-12 (2010)

Background Reference 02

Rajagopalan, S., et al. J. Biol. Chem. 284 (32) :21728-21737 (2009)

Background Reference 03

Mortusewicz, O., et al. J. Cell Biol. 183 (5) :769-776 (2008)

Background Reference 04

Batta, K., et al. Mol. Cell. Biol. 27 (21) :7603-7614 (2007)

Other Product Names

Activated RNA polymerase II transcriptional coactivator p15, Positive cofactor 4, PC4, SUB1 homolog, p14, SUB1, PC4, RPO2TC1

Tested Applications

Protein ID

1709514

Physical Properties

Liquid

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