SMAD5 Antibody

Product Specifications

Background

Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD) .

NCBI Gene ID

4090

Swiss Prot

Q99717

Accession Number

Q99717

Host

Rabbit

Reactivity

Human

Immunogen

This SMAD5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 241-269 amino acids from the Central region of human SMAD5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

52 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SMAD5

NCBI Official Name

Mothers against decapentaplegic homolog 5

NCBI Organism

Homo sapiens

Background Reference 01

Yang, J., et al. Circ. Res. 107 (2) :252-262 (2010)

Background Reference 02

Tao, S., et al. Dev. Growth Differ. 52 (4) :335-342 (2010)

Background Reference 03

Middlebrook, B.S., et al. Endocrinology 150 (12) :5208-5217 (2009)

Background Reference 04

Su, D., et al. J. Biol. Chem. 284 (18) :12153-12164 (2009)

Other Product Names

Mothers against decapentaplegic homolog 5, MAD homolog 5, Mothers against DPP homolog 5, JV5-1, SMAD family member 5, SMAD 5, Smad5, hSmad5, SMAD5, MADH5