GRIN2C Antibody

Product Specifications

Background

N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D) . [provided by RefSeq].

NCBI Gene ID

2905

Swiss Prot

Q14957

Accession Number

Q14957

Host

Rabbit

Reactivity

Mouse

Immunogen

This GRIN2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 567-595 amino acids from the Central region of human GRIN2C.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

134 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

GRIN2C

NCBI Official Name

Glutamate receptor ionotropic, NMDA 2C

NCBI Organism

Homo sapiens

Background Reference 01

Need, A.C., et al. Eur. J. Hum. Genet. 17 (7) :946-957 (2009)

Background Reference 02

Tabakoff, B., et al. BMC Biol. 7, 70 (2009) :

Background Reference 03

Shi, J., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 147B (7), 1270-1277 (2008) :

Background Reference 04

Self, R.L., et al. Brain Res. 995 (1) :39-45 (2004)

Other Product Names

Glutamate receptor ionotropic, NMDA 2C, GluN2C, Glutamate [NMDA] receptor subunit epsilon-3, N-methyl D-aspartate receptor subtype 2C, NMDAR2C, NR2C, GRIN2C, NMDAR2C