TFAP2A Antibody
Product Specifications
Background
TFAP2A is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. TFAP2A is the only AP-2 protein required for early morphogenesis of the lens vesicle.
NCBI Gene ID
7020
Swiss Prot
P05549
Accession Number
P05549
Host
Rabbit
Reactivity
Human
Immunogen
This TFAP2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 407-436 amino acids from the C-terminal region of human TFAP2A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=60-706
Calculated Molecular Weight
48 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
TFAP2A
NCBI Official Name
Transcription factor AP-2-alpha
NCBI Organism
Homo sapiens
Background Reference 01
Provenzano, M.J., Exp. Mol. Pathol. 83 (2), 277-282 (2007)
Background Reference 02
Tan, Y.R., Biochem. J. 405 (1), 131-137 (2007)
Background Reference 03
Liu, H., EMBO Rep. (4), 394-400 (2007)
Background Reference 04
Han, S., J. Biol. Chem. 282 (11), 7961-7972 (2007)
Other Product Names
Transcription factor AP-2-alpha, AP2-alpha, AP-2 transcription factor, Activating enhancer-binding protein 2-alpha, Activator protein 2, AP-2, TFAP2A, AP2TF, TFAP2
Tested Applications
WB
Protein ID
135302
Physical Properties
Liquid
Curated Selection
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