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PRRX2 Antibody

Product Specifications

Background

The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation.

NCBI Gene ID

51450

Swiss Prot

Q99811

Accession Number

Q99811

Host

Rabbit

Reactivity

Mouse

Immunogen

This PRRX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-250 amino acids from the C-terminal region of human PRRX2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=60-703

Calculated Molecular Weight

27 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PRRX2

NCBI Official Name

Paired mesoderm homeobox protein 2

NCBI Organism

Homo sapiens

Background Reference 01

Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :

Background Reference 02

Eriksson, N., et al. PLoS Genet. (6), E1000993 (2010) :

Background Reference 03

Tokutomi, Y., et al. Biochem. Biophys. Res. Commun. 364 (4) :822-830 (2007)

Background Reference 04

Wissmuller, S., et al. Nucleic Acids Res. 34 (6) :1735-1744 (2006)

Other Product Names

Paired mesoderm homeobox protein 2, Paired-related homeobox protein 2, PRX-2, PRRX2, PMX2, PRX2

Tested Applications

WB

Protein ID

12644475

Physical Properties

Liquid

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