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UBE2R2 Antibody

Product Specifications

Background

Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation.

NCBI Gene ID

54926

Swiss Prot

Q712K3

Accession Number

Q712K3

Host

Rabbit

Reactivity

Human

Immunogen

This UBE2R2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 141-169 amino acids from the Central region of human UBE2R2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rabbit

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=60-700

Calculated Molecular Weight

27 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

UBE2R2

NCBI Official Name

Ubiquitin-conjugating enzyme E2 R2

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 02

Yoshida, T., et al. Int. J. Mol. Med. 25 (4) :649-656 (2010)

Background Reference 03

Oguri, M., et al. Am. J. Hypertens. 23 (1) :70-77 (2010)

Background Reference 04

Ferreira, M.A., et al. Nat. Genet. 40 (9) :1056-1058 (2008)

Other Product Names

Ubiquitin-conjugating enzyme E2 R2, Ubiquitin carrier protein R2, Ubiquitin-conjugating enzyme E2-CDC34B, Ubiquitin-protein ligase R2, UBE2R2, CDC34B, UBC3B

Tested Applications

WB

Protein ID

74749761

Physical Properties

Liquid

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