SETD1A Antibody
Product Specifications
Background
SET1A is a component of a histone methyltransferase (HMT) complex that produces mono-, di-, and trimethylated histone H3 at Lys4. The complex is the analog of the S. cerevisiae Set1/COMPASS complex (Lee and Skalnik, 2005 [PubMed 16253997]) . Also see SET1B (MIM 611055) .
NCBI Gene ID
9739
Swiss Prot
O15047
Accession Number
O15047
Host
Rabbit
Reactivity
Human
Immunogen
This SETD1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 927-956 amino acids from the Central region of human SETD1A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=60-677
Calculated Molecular Weight
186 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SETD1A
NCBI Official Name
Histone-lysine N-methyltransferase SETD1A
NCBI Organism
Homo sapiens
Background Reference 01
Wu, M., et al. Mol. Cell. Biol. 28 (24) :7337-7344 (2008)
Background Reference 02
Nguyen, P., et al. Mol. Cell. Biol. 28 (21) :6720-6729 (2008)
Background Reference 03
Ansari, K.I., et al. Biochim. Biophys. Acta 1779 (1) :66-73 (2008)
Background Reference 04
Lee, J.H., et al. Mol. Cell. Biol. 28 (2) :609-618 (2008)
Other Product Names
Histone-lysine N-methyltransferase SETD1A, Lysine N-methyltransferase 2F, SET domain-containing protein 1A, hSET1A, Set1/Ash2 histone methyltransferase complex subunit SET1, SETD1A
Tested Applications
WB
Physical Properties
Liquid
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