Mouse Senp1 Antibody
Product Specifications
Background
Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. Deconjugates SUMO1 from HIPK2. Deconjugates SUMO1 from HDAC1, which decreases its transcriptional repression activity.
NCBI Gene ID
223870
Swiss Prot
P59110
Accession Number
P59110
Host
Rabbit
Reactivity
Mouse
Immunogen
This Mouse Senp1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-289 amino acids from the Central region of mouse Senp1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
73 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
Senp1
NCBI Official Name
Sentrin-specific protease 1
NCBI Organism
Mus musculus
Background Reference 01
Bawa-Khalfe, T., et al. J. Biol. Chem. 285 (33) :25859-25866 (2010)
Background Reference 02
Yu, L., et al. J. Exp. Med. 207 (6) :1183-1195 (2010)
Background Reference 03
Sharma, P., et al. J. Cell. Sci. 123 (PT 8), 1227-1234 (2010) :
Background Reference 04
Li, X., et al. Cell Death Differ. 15 (4) :739-750 (2008)
Other Product Names
Sentrin-specific protease 1, SUMO-1 protease 2, SuPr-2, Sentrin/SUMO-specific protease SENP1, Senp1, Supr2
Tested Applications
WB
Physical Properties
Liquid
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