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Mouse Senp1 Antibody

Product Specifications

Background

Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. Deconjugates SUMO1 from HIPK2. Deconjugates SUMO1 from HDAC1, which decreases its transcriptional repression activity.

NCBI Gene ID

223870

Swiss Prot

P59110

Accession Number

P59110

Host

Rabbit

Reactivity

Mouse

Immunogen

This Mouse Senp1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-289 amino acids from the Central region of mouse Senp1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=60-665

Calculated Molecular Weight

73 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

Senp1

NCBI Official Name

Sentrin-specific protease 1

NCBI Organism

Mus musculus

Background Reference 01

Bawa-Khalfe, T., et al. J. Biol. Chem. 285 (33) :25859-25866 (2010)

Background Reference 02

Yu, L., et al. J. Exp. Med. 207 (6) :1183-1195 (2010)

Background Reference 03

Sharma, P., et al. J. Cell. Sci. 123 (PT 8), 1227-1234 (2010) :

Background Reference 04

Li, X., et al. Cell Death Differ. 15 (4) :739-750 (2008)

Other Product Names

Sentrin-specific protease 1, SUMO-1 protease 2, SuPr-2, Sentrin/SUMO-specific protease SENP1, Senp1, Supr2

Tested Applications

WB

Physical Properties

Liquid

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