PRPS1L1 Antibody

Product Specifications

Background

This intronless gene is specifically expressed in the testis, and encodes a protein that is highly homologous to the two subunits of phosphoribosylpyrophosphate synthetase encoded by human X-linked genes, PRPS1 and PRPS2. These enzymes convert pyrimidine, purine or pyridine bases to the corresponding ribonucleoside monophosphates. In vitro transcription/translation and site-directed mutagenesis studies indicate that translation of this mRNA initiates exclusively at a non-AUG (ACG) codon. [provided by RefSeq].

NCBI Gene ID

221823

Swiss Prot

P21108

Accession Number

P21108

Host

Rabbit

Reactivity

Human

Immunogen

This PRPS1L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-106 amino acids from the N-terminal region of human PRPS1L1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

35 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PRPS1L1

NCBI Official Name

Ribose-phosphate pyrophosphokinase 3

NCBI Organism

Homo sapiens

Background Reference 01

Venter, J.C., et al. Science 291 (5507) :1304-1351 (2001)

Background Reference 02

Taira, M., et al. J. Biol. Chem. 265 (27) :16491-16497 (1990)

Other Product Names

Ribose-phosphate pyrophosphokinase 3, Phosphoribosyl pyrophosphate synthase 1-like 1, PRPS1-like 1, Phosphoribosyl pyrophosphate synthase III, PRS-III, PRPS1L1, PRPS3, PRPSL