MEFV Antibody
Product Specifications
Background
This gene encodes a protein, also known as pyrin or marenostrin, that is an important modulator of innate immunity. Mutations in this gene are associated with Mediterranean fever, a hereditary periodic fever syndrome.
NCBI Gene ID
4210
Swiss Prot
O15553
Accession Number
O15553
Host
Rabbit
Reactivity
Human
Immunogen
This MEFV antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 418-445 amino acids from the Central region of human MEFV.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
86 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MEFV
NCBI Official Name
Pyrin
NCBI Organism
Homo sapiens
Background Reference 01
Cosan, F., et al. Arthritis Rheum. 62 (11) :3232-3236 (2010)
Background Reference 02
Shimada, M., et al. Hum. Genet. 128 (4) :433-441 (2010)
Background Reference 03
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 04
He, X., et al. Pediatr. Nephrol. 25 (10) :2077-2082 (2010)
Other Product Names
Pyrin, Marenostrin, MEFV, MEF
Tested Applications
WB
Physical Properties
Liquid
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