ZNF185 Antibody
Product Specifications
Background
Zinc-finger proteins bind nucleic acids and play important roles in various cellular functions, including cell proliferation, differentiation, and apoptosis. This gene encodes a LIM-domain zinc finger protein. The LIM domain is composed of two contiguous zinc finger domains, separated by a two-amino acid residue hydrophobic linker. The LIM domain mediates protein:protein interactions. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
NCBI Gene ID
7739
Swiss Prot
O15231
Accession Number
O15231
Host
Rabbit
Reactivity
Human
Immunogen
This ZNF185 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 155-183 amino acids from the N-terminal region of human ZNF185.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
74 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ZNF185
NCBI Official Name
Zinc finger protein 185
NCBI Organism
Homo sapiens
Background Reference 01
Zhang, J.S., et al. Oncogene 26 (1) :111-122 (2007)
Background Reference 02
Medina, P.P., et al. Hum. Mol. Genet. 14 (7) :973-982 (2005)
Background Reference 03
Vanaja, D.K., et al. Cancer Res. 63 (14) :3877-3882 (2003)
Background Reference 04
Mallon, A.M., et al. Genome Res. 10 (6) :758-775 (2000)
Other Product Names
Zinc finger protein 185, LIM domain protein ZNF185, P1-A, ZNF185
Tested Applications
WB
Physical Properties
Liquid
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