Mouse Shc4 Antibody

Product Specifications

Background

Activates both Ras-dependent and Ras-independent migratory pathways in melanomas. Contributes to the early phases of agrin-induced tyrosine phosphorylation of CHRNB1.

NCBI Gene ID

271849

Swiss Prot

Q6S5L9

Accession Number

Q6S5L9

Host

Rabbit

Reactivity

Mouse

Immunogen

This Mouse Shc4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 590-617 amino acids from the C-terminal region of mouse Shc4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

69 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

Shc4

NCBI Official Name

SHC-transforming protein 4

NCBI Organism

Mus musculus

Background Reference 01

Jones, N., et al. Mol. Cell. Biol. 27 (13) :4759-4773 (2007)

Background Reference 02

Fagiani, E., et al. Cancer Res. 67 (7) :3064-3073 (2007)

Other Product Names

SHC-transforming protein 4, Rai-like protein, RaLP, SHC-transforming protein D, mShcD, Src homology 2 domain-containing-transforming protein C4, SH2 domain protein C4, Shc4, Shcd