HBZ Antibody
Product Specifications
Background
Zeta-globin is an alpha-like hemoglobin. The zeta-globin polypeptide is synthesized in the yolk sac of the early embryo, while alpha-globin is produced throughout fetal and adult life. The zeta-globin gene is a member of the human alpha-globin gene cluster that includes five functional genes and two pseudogenes. The order of genes is: 5' - zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 -alpha-1 - theta1 - 3'.
NCBI Gene ID
3050
Swiss Prot
P02008
Accession Number
P02008
Host
Rabbit
Reactivity
Human
Immunogen
This HBZ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-123 amino acids from the C-terminal region of human HBZ.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
16 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
HBZ
NCBI Official Name
Hemoglobin subunit zeta
NCBI Organism
Homo sapiens
Background Reference 01
Hivin, P., et al. J. Cell. Sci. 118 (PT 7), 1355-1362 (2005) :
Background Reference 02
He, Z., et al. Biochem. Biophys. Res. Commun. 325 (4) :1376-1382 (2004)
Background Reference 03
Kidd, R.D., et al. Biochemistry 40 (51) :15669-15675 (2001)
Background Reference 04
Lau, E.T., et al. Prenat. Diagn. 21 (7) :529-539 (2001)
Other Product Names
Hemoglobin subunit zeta, HBAZ, Hemoglobin zeta chain, Zeta-globin, HBZ, HBZ2
Tested Applications
WB
Protein ID
122335
Physical Properties
Liquid
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