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GSTT2 Antibody

Product Specifications

Background

Glutathione S-transferase (GSTs) theta 2 (GSTT2) is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: Alpha, Mu, Pi, Theta, and Zeta. The theta class members GSTT1 and GSTT2 share 55% amino acid sequence identity and both are thought to have an important role in human carcinogenesis. The theta genes have a similar structure, being composed of five exons with identical exon/intron boundaries.

NCBI Gene ID

2953

Swiss Prot

P0CG29

Accession Number

P0CG29

Host

Rabbit

Reactivity

Human

Immunogen

This GSTT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 113-141 amino acids from the Central region of human GSTT2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

28 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

GSTT2

NCBI Official Name

Glutathione S-transferase theta-2

NCBI Organism

Homo sapiens

Background Reference 01

Moyer, A.M., et al. Cancer Epidemiol. Biomarkers Prev. 19 (3) :811-821 (2010)

Background Reference 02

Canova, C., et al. Tumori 96 (1) :1-10 (2010)

Background Reference 03

Wang, S., et al. Ann. Hum. Genet. 74 (1) :46-56 (2010)

Background Reference 04

Gemignani, F., et al. Mutat. Res. 671 (1-2), 76-83 (2009) :

Other Product Names

Glutathione S-transferase theta-2, GST class-theta-2, GSTT2

Tested Applications

WB

Protein ID

300680960

Physical Properties

Liquid

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