GTPBP3 Antibody

Product Specifications

Background

This locus encodes a GTP-binding protein. The encoded protein is localized to the mitochondria and may play a role in mitochondrial tRNA modification. Polymorphisms at this locus may be associated with severity of aminoglycoside-induced deafness, a disease associated with a mutation in the 12S rRNA. Alternatively spliced transcript variants encoding different isoforms have been described.

NCBI Gene ID

84705

Swiss Prot

Q969Y2

Accession Number

Q969Y2

Host

Rabbit

Reactivity

Human

Immunogen

This GTPBP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 293-320 amino acids from the Central region of human GTPBP3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

52 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

GTPBP3

NCBI Official Name

TRNA modification GTPase GTPBP3, mitochondrial

NCBI Organism

Homo sapiens

Background Reference 01

Reiling, E., et al. Eur. J. Hum. Genet. 17 (8) :1056-1062 (2009)

Background Reference 02

Villarroya, M., et al. Mol. Cell. Biol. 28 (24) :7514-7531 (2008)

Background Reference 03

Bykhovskaya, Y., et al. Mol. Genet. Metab. 83 (3) :199-206 (2004)

Background Reference 04

Li, X., et al. Biochem. Biophys. Res. Commun. 312 (3) :747-754 (2003)

Other Product Names

TRNA modification GTPase GTPBP3, mitochondrial, GTP-binding protein 3, Mitochondrial GTP-binding protein 1, GTPBP3, MTGP1

Tested Applications

Protein ID

313104112

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MBS2577604-01 1 Pair

Human MMP-3 Antibody Pair Set

Ask

View Details

MBS2577604-02 5x 1 Pair

Human MMP-3 Antibody Pair Set

Ask

View Details

NB100-1576AF532 0.1 mL

Rabbit Polyclonal DDX10 Antibody [Alexa Fluor 532]

Ask

View Details

MBS8298884-01 5 nmol

hsa-miR-1539 miRNA Mimic

Ask

View Details

MBS8298884-02 10 nmol

hsa-miR-1539 miRNA Mimic

Ask

View Details

MBS8298884-03 5x 10 nmol

hsa-miR-1539 miRNA Mimic

Ask

View Details