UBR7 Antibody
Product Specifications
Background
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific amino-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation (By similarity) .
NCBI Gene ID
55148
Swiss Prot
Q8N806
Accession Number
Q8N806
Host
Rabbit
Reactivity
Human
Immunogen
This UBR7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 100-128 amino acids from the N-terminal region of human UBR7.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
48 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
UBR7
NCBI Official Name
Putative E3 ubiquitin-protein ligase UBR7
NCBI Organism
Homo sapiens
Background Reference 01
Lee, M.J., et al. Proc. Natl. Acad. Sci. U.S.A. 105 (1) :100-105 (2008)
Background Reference 02
Lim, J., et al. Cell 125 (4) :801-814 (2006)
Other Product Names
Putative E3 ubiquitin-protein ligase UBR7, 632-, N-recognin-7, UBR7, C14orf130
Tested Applications
WB
Protein ID
37999713
Physical Properties
Liquid
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