RECQL4 Antibody
Product Specifications
Background
The protein encoded by this gene is a DNA helicase that belongs to the RecQ helicase family. DNA helicases unwind double-stranded DNA into single-stranded DNAs and may modulate chromosome segregation. This gene is predominantly expressed in thymus and testis. Mutations in this gene are associated with Rothmund-Thomson, RAPADILINO and Baller-Gerold syndromes. [provided by RefSeq].
NCBI Gene ID
9401
Swiss Prot
O94761
Accession Number
O94761
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This RECQL4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1134-1162 amino acids from the C-terminal region of human RECQL4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
133 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
RECQL4
NCBI Official Name
ATP-dependent DNA helicase Q4
NCBI Organism
Homo sapiens
Background Reference 01
Rossi, M.L., et al. DNA Repair (Amst.) 9 (7) :796-804 (2010)
Background Reference 02
Singh, D.K., et al. Aging Cell 9 (3) :358-371 (2010)
Background Reference 03
Thangavel, S., et al. Mol. Cell. Biol. 30 (6) :1382-1396 (2010)
Background Reference 04
Xu, X., et al. EMBO J. 28 (19) :3005-3014 (2009)
Other Product Names
ATP-dependent DNA helicase Q4, DNA helicase, RecQ-like type 4, RecQ4, RTS, RecQ protein-like 4, RECQL4, RECQ4
Tested Applications
WB
Physical Properties
Liquid
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