RECQL4 Antibody

Product Specifications

Background

The protein encoded by this gene is a DNA helicase that belongs to the RecQ helicase family. DNA helicases unwind double-stranded DNA into single-stranded DNAs and may modulate chromosome segregation. This gene is predominantly expressed in thymus and testis. Mutations in this gene are associated with Rothmund-Thomson, RAPADILINO and Baller-Gerold syndromes. [provided by RefSeq].

NCBI Gene ID

9401

Swiss Prot

O94761

Accession Number

O94761

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This RECQL4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1134-1162 amino acids from the C-terminal region of human RECQL4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

133 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

RECQL4

NCBI Official Name

ATP-dependent DNA helicase Q4

NCBI Organism

Homo sapiens

Background Reference 01

Rossi, M.L., et al. DNA Repair (Amst.) 9 (7) :796-804 (2010)

Background Reference 02

Singh, D.K., et al. Aging Cell 9 (3) :358-371 (2010)

Background Reference 03

Thangavel, S., et al. Mol. Cell. Biol. 30 (6) :1382-1396 (2010)

Background Reference 04

Xu, X., et al. EMBO J. 28 (19) :3005-3014 (2009)

Other Product Names

ATP-dependent DNA helicase Q4, DNA helicase, RecQ-like type 4, RecQ4, RTS, RecQ protein-like 4, RECQL4, RECQ4

Tested Applications

Physical Properties

Liquid

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