GUCA1B Antibody

Product Specifications

Background

The protein encoded by this gene is a calcium-binding protein that activates photoreceptor guanylate cyclases. This gene may have arisen due to a gene duplication event since there is a highly similar gene clustered with it on chromosome 6. Mutations in this gene can cause a form of retinitis pigmentosa. [provided by RefSeq].

NCBI Gene ID

2979

Swiss Prot

Q9UMX6

Accession Number

Q9UMX6

Host

Rabbit

Reactivity

Human

Immunogen

This GUCA1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-57 amino acids from the N-terminal region of human GUCA1B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

23 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

GUCA1B

NCBI Official Name

Guanylyl cyclase-activating protein 2

NCBI Organism

Homo sapiens

Background Reference 01

Sato, M., et al. Graefes Arch. Clin. Exp. Ophthalmol. 243 (3) :235-242 (2005)

Background Reference 02

Nishiguchi, K.M., et al. Invest. Ophthalmol. Vis. Sci. 45 (11) :3863-3870 (2004)

Background Reference 03

Mungall, A.J., et al. Nature 425 (6960) :805-811 (2003)

Background Reference 04

Wistow, G., et al. Mol. Vis. 8, 196-204 (2002) :

Other Product Names

Guanylyl cyclase-activating protein 2, GCAP 2, Guanylate cyclase activator 1B, GUCA1B, GCAP2

Tested Applications

Protein ID

116242507

Physical Properties

Liquid

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