Mouse Pbk Antibody

Product Specifications

Background

Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization (By similarity) .

NCBI Gene ID

52033

Swiss Prot

Q9JJ78

Accession Number

Q9JJ78

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This Mouse Pbk antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-86 amino acids from the N-terminal region of mouse Pbk.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

37 kDa

Fragment

Rabbit Ig

Symbol

Pbk

NCBI Official Name

Lymphokine-activated killer T-cell-originated protein kinase

NCBI Organism

Mus musculus

Background Reference 01

Zykova, T.A., et al. Clin. Cancer Res. 12 (23) :6884-6893 (2006)

Background Reference 02

Fujibuchi, T., et al. Dev. Growth Differ. 47 (9) :637-644 (2005)

Background Reference 03

Blackshaw, S., et al. PLoS Biol. (9), E247 (2004) :

Background Reference 04

Visel, A., et al. Nucleic Acids Res. 32 (DATABASE ISSUE), D552-D556 (2004) :

Other Product Names

Lymphokine-activated killer T-cell-originated protein kinase, PDZ-binding kinase, T-LAK cell-originated protein kinase, Pbk, Topk

Tested Applications

WB, IHC-P, Flow

Physical Properties

Liquid

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