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Cleavage stimulation factor 2 Antibody

Product Specifications

Background

CSTF2 is one of three (including CSTF1 and CSTF3) cleavage stimulation factors which combine to form CSTF which is involved in the polyadenylation and 3'end cleavage of pre-mRNAs. CSTF2 contains a ribonucleoprotein-type RNA binding domain. CSTF2 is upregulated during activation of B cells which results in the switch of IgM heavy chain mRNA from membrane bound form to the secreted form.

NCBI Gene ID

1478

Swiss Prot

P33240

Accession Number

P33240

Host

Rabbit

Reactivity

Human

Immunogen

This Cleavage stimulation factor 2 (CSTF2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-60 amino acids from the N-terminal region of human Cleavage stimulation factor 2 (CSTF2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

61 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CSTF2

NCBI Official Name

Cleavage stimulation factor subunit 2

NCBI Organism

Homo sapiens

Background Reference 01

Takagaki, Y., et al., Mol. Cell 2 (6) :761-771 (1998) .

Background Reference 02

Martincic, K., et al., Proc. Natl. Acad. Sci. U.S.A. 95 (19) :11095-11100 (1998) .

Background Reference 03

Takagaki, Y., et al., Cell 87 (5) :941-952 (1996) .

Background Reference 04

Takagaki, Y., et al., Nature 372 (6505) :471-474 (1994) .

Other Product Names

Cleavage stimulation factor subunit 2, CF-1 64 kDa subunit, Cleavage stimulation factor 64 kDa subunit, CSTF 64 kDa subunit, CstF-64, CSTF2

Tested Applications

WB

Protein ID

461847

Physical Properties

Liquid

Frequently Asked Questions

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