Mouse Dyrk1a Antibody

Product Specifications

Background

Dyrk1a may play a role in a signaling pathway regulating nuclear functions of cell proliferation. Phosphorylates serine, threonine and tyrosine residues in its sequence and in exogenous substrates.

NCBI Gene ID

13548

Swiss Prot

Q61214

Accession Number

Q61214

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This Mouse Dyrk1a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 718-745 amino acids from the C-terminal region of mouse Dyrk1a.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

85 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

Dyrk1a

NCBI Official Name

Dual specificity tyrosine-phosphorylation-regulated kinase 1A

NCBI Organism

Mus musculus

Background Reference 01

Park, J., et al. J. Biol. Chem. 285 (41) :31895-31906 (2010)

Background Reference 02

Guo, X., et al. J. Biol. Chem. 285 (17) :13223-13232 (2010)

Background Reference 03

Kurabayashi, N., et al. Mol. Cell. Biol. 30 (7) :1757-1768 (2010)

Background Reference 04

Lee, Y., et al. J. Biol. Chem. 284 (48) :33343-33351 (2009)

Other Product Names

Dual specificity tyrosine-phosphorylation-regulated kinase 1A, Dual specificity YAK1-related kinase, MP86, Protein kinase minibrain homolog, MNBH, Dyrk1a, Dyrk