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DHODH Antibody

Product Specifications

Background

The protein encoded by this gene catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane.

NCBI Gene ID

1723

Swiss Prot

Q02127

Accession Number

Q02127

Host

Rabbit

Reactivity

Human

Immunogen

This DHODH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-194 amino acids from the Central region of human DHODH.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

43 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

DHODH

NCBI Official Name

Dihydroorotate dehydrogenase (quinone), mitochondrial

NCBI Organism

Homo sapiens

Background Reference 01

Hail, N. Jr., et al. Free Radic. Biol. Med. 49 (1) :109-116 (2010)

Background Reference 02

Ng, S.B., et al. Nat. Genet. 42 (1) :30-35 (2010)

Background Reference 03

Grabar, P.B., et al. Ann. Rheum. Dis. 68 (8) :1367-1368 (2009)

Background Reference 04

Pawlik, A., et al. Pharmacogenomics 10 (2) :303-309 (2009)

Other Product Names

Dihydroorotate dehydrogenase (quinone), mitochondrial, DHOdehase, Dihydroorotate oxidase, DHODH

Tested Applications

WB

Protein ID

56405372

Physical Properties

Liquid

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