CCDC6 Antibody

Product Specifications

Background

This gene encodes a coiled-coil domain-containing protein. The encoded protein is ubiquitously expressed and may function as a tumor suppressor. A chromosomal rearrangement resulting in the expression of a fusion gene containing a portion of this gene and the intracellular kinase-encoding domain of the ret proto-oncogene is the cause of thyroid papillary carcinoma.

NCBI Gene ID

8030

Swiss Prot

Q16204

Accession Number

Q16204

Host

Rabbit

Reactivity

Human

Immunogen

This CCDC6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-82 amino acids from the N-terminal region of human CCDC6.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

53 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CCDC6

NCBI Official Name

Coiled-coil domain-containing protein 6

NCBI Organism

Homo sapiens

Background Reference 01

Leone, V., et al. Oncogene 29 (30) :4341-4351 (2010)

Background Reference 02

Richardson, D.S., et al. Cancer Res. 69 (11) :4861-4869 (2009)

Background Reference 03

Jazdzewski, K., et al. Proc. Natl. Acad. Sci. U.S.A. 105 (20) :7269-7274 (2008)

Background Reference 04

Sugiyama, N., et al. Mol. Cell Proteomics 6 (6) :1103-1109 (2007)

Other Product Names

Coiled-coil domain-containing protein 6, Papillary thyroid carcinoma-encoded protein, Protein H4, CCDC6, D10S170, TST1

Tested Applications

Protein ID

292494979

Physical Properties

Liquid

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