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SSH1 Antibody

Product Specifications

Background

The ADF (actin-depolymerizing factor) /cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329) . The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002 [PubMed 11832213]) .

NCBI Gene ID

54434

Swiss Prot

Q8WYL5

Accession Number

Q8WYL5

Host

Rabbit

Reactivity

Human

Immunogen

This SSH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-254 amino acids from the N-terminal region of human SSH1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

116 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SSH1

NCBI Official Name

Protein phosphatase Slingshot homolog 1

NCBI Organism

Homo sapiens

Background Reference 01

Song, S.Y., et al. APMIS 118 (5) :389-393 (2010)

Background Reference 02

Peterburs, P., et al. Cancer Res. 69 (14) :5634-5638 (2009)

Background Reference 03

Kligys, K., et al. Biochem. Biophys. Res. Commun. 383 (4) :450-454 (2009)

Background Reference 04

Kim, J.S., et al. Mol. Biol. Cell 20 (11) :2650-2660 (2009)

Other Product Names

Protein phosphatase Slingshot homolog 1, SSH-like protein 1, SSH-1L, hSSH-1L, SSH1, KIAA1298, SSH1L

Tested Applications

WB

Protein ID

82582267

Physical Properties

Liquid

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