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ILKAP Antibody

Product Specifications

Background

The protein encoded by this gene is a protein serine/threonine phosphatase of the PP2C family. This protein can interact with integrin-linked kinase (ILK/ILK1), a regulator of integrin mediated signaling, and regulate the kinase activity of ILK. Through the interaction with ILK, this protein may selectively affect the signaling process of ILK-mediated glycogen synthase kinase 3 beta (GSK3beta), and thus participate in Wnt signaling pathway.

NCBI Gene ID

80895

Swiss Prot

Q9H0C8

Accession Number

Q9H0C8

Host

Rabbit

Reactivity

Human

Immunogen

This ILKAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-122 amino acids from the Central region of human ILKAP.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=60-521

Calculated Molecular Weight

43 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ILKAP

NCBI Official Name

Integrin-linked kinase-associated serine/threonine phosphatase 2C

NCBI Organism

Homo sapiens

Background Reference 01

Nakrieko, K.A., et al. Cell Cycle 7 (14) :2157-2166 (2008)

Background Reference 02

Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

Background Reference 03

Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

Background Reference 04

Hillier, L.W., et al. Nature 434 (7034) :724-731 (2005)

Other Product Names

Integrin-linked kinase-associated serine/threonine phosphatase 2C, ILKAP, ILKAP

Tested Applications

WB

Protein ID

74752560

Physical Properties

Liquid

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