COL10A1 Antibody
Product Specifications
Background
This gene encodes the alpha chain of type X collagen, a short chain collagen expressed by hypertrophic chondrocytes during endochondral ossification. Unlike type VIII collagen, the other short chain collagen, type X collagen is a homotrimer. Mutations in this gene are associated with Schmid type metaphyseal chondrodysplasia (SMCD) and Japanese type spondylometaphyseal dysplasia (SMD) .
NCBI Gene ID
1300
Swiss Prot
Q03692
Accession Number
Q03692
Host
Rabbit
Reactivity
Human
Immunogen
This COL10A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-58 amino acids from the N-terminal region of human COL10A1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
66 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
COL10A1
NCBI Official Name
Collagen alpha-1 (X) chain
NCBI Organism
Homo sapiens
Background Reference 01
Makitie, O., et al. J. Orthop. Res. 28 (11) :1497-1501 (2010)
Background Reference 02
Wang, S., et al. Connect. Tissue Res. 51 (3) :188-196 (2010)
Background Reference 03
Videman, T., et al. Arthritis Rheum. 60 (2) :470-481 (2009)
Background Reference 04
Higashikawa, A., et al. Arthritis Rheum. 60 (1) :166-178 (2009)
Other Product Names
Collagen alpha-1 (X) chain, COL10A1
Tested Applications
WB
Protein ID
2506306
Physical Properties
Liquid
Curated Selection
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