RALBP1 Antibody

Product Specifications

Background

RALBP1 plays a role in receptor-mediated endocytosis and is a downstream effector of the small GTP-binding protein RAL (see RALA; MIM 179550) . Small G proteins, such as RAL, have GDP-bound inactive and GTP-bound active forms, which shift from the inactive to the active state through the action of RALGDS (MIM 601619), which in turn is activated by RAS (see HRAS; MIM 190020) (summary by Feig, 2003 [PubMed 12888294]) .

NCBI Gene ID

10928

Swiss Prot

Q15311

Accession Number

Q15311

Host

Rabbit

Reactivity

Human

Immunogen

This RALBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-71 amino acids from the N-terminal region of human RALBP1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Immunology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

76 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

RALBP1

NCBI Official Name

RalA-binding protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Singhal, S.S., et al. Int. J. Cancer 126 (6) :1327-1338 (2010)

Background Reference 02

Singhal, S.S., et al. Cancer Lett. 283 (2) :152-158 (2009)

Background Reference 03

Awasthi, Y.C., et al.Toxicol Environ HealthCrit Rev 12 (7) :540-551 (2009)

Background Reference 04

Singhal, S.S., et al. Cancer Res. 69 (10) :4244-4251 (2009)

Other Product Names

RalA-binding protein 1, RalBP1, 76 kDa Ral-interacting protein, Dinitrophenyl S-glutathione ATPase, DNP-SG ATPase, Ral-interacting protein 1, RALBP1, RLIP1, RLIP76