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BRMS1 Antibody

Product Specifications

Background

This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC) . The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.

NCBI Gene ID

25855

Swiss Prot

Q9HCU9

Accession Number

Q9HCU9

Host

Rabbit

Reactivity

Human

Immunogen

This BRMS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-77 amino acids from the N-terminal region of human BRMS1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

28 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

BRMS1

NCBI Official Name

Breast cancer metastasis-suppressor 1

NCBI Organism

Homo sapiens

Background Reference 01

Wu, Y., et al. Cancer Lett. 293 (1) :82-91 (2010)

Background Reference 02

Vaidya, K.S., et al. Cancer Lett. 281 (1) :100-107 (2009)

Background Reference 03

Frolova, N., et al. Tumour Biol. 30 (3) :148-159 (2009)

Background Reference 04

Martins-de-Souza, D., et al. BMC Psychiatry 9, 17 (2009) :

Other Product Names

Breast cancer metastasis-suppressor 1, BRMS1

Tested Applications

WB

Protein ID

18202959

Physical Properties

Liquid

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