BRMS1 Antibody
Product Specifications
Background
This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC) . The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.
NCBI Gene ID
25855
Swiss Prot
Q9HCU9
Accession Number
Q9HCU9
Host
Rabbit
Reactivity
Human
Immunogen
This BRMS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-77 amino acids from the N-terminal region of human BRMS1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
28 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
BRMS1
NCBI Official Name
Breast cancer metastasis-suppressor 1
NCBI Organism
Homo sapiens
Background Reference 01
Wu, Y., et al. Cancer Lett. 293 (1) :82-91 (2010)
Background Reference 02
Vaidya, K.S., et al. Cancer Lett. 281 (1) :100-107 (2009)
Background Reference 03
Frolova, N., et al. Tumour Biol. 30 (3) :148-159 (2009)
Background Reference 04
Martins-de-Souza, D., et al. BMC Psychiatry 9, 17 (2009) :
Other Product Names
Breast cancer metastasis-suppressor 1, BRMS1
Tested Applications
WB
Protein ID
18202959
Physical Properties
Liquid
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