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RNF135 Antibody

Product Specifications

Background

The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. This gene is located in a chromosomal region known to be frequently deleted in patients with neurofibromatosis. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq].

NCBI Gene ID

84282

Swiss Prot

Q8IUD6

Accession Number

Q8IUD6

Host

Rabbit

Reactivity

Human

Immunogen

This RNF135 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 375-401 amino acids from the C-terminal region of human RNF135.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

48 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:500

Symbol

RNF135

NCBI Official Name

E3 ubiquitin-protein ligase RNF135

NCBI Organism

Homo sapiens

Background Reference 01

Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :

Background Reference 02

You, F., et al. Nat. Immunol. 10 (12) :1300-1308 (2009)

Background Reference 03

Visser, R., et al. Am. J. Med. Genet.149A (4), 806-808 (2009) :

Background Reference 04

Oshiumi, H., et al. J. Biol. Chem. 284 (2) :807-817 (2009)

Other Product Names

E3 ubiquitin-protein ligase RNF135, 632-, RIG-I E3 ubiquitin ligase, REUL, RING finger protein 135, Riplet, RNF135

Tested Applications

WB

Protein ID

269849639

Physical Properties

Liquid

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