SYT4 Antibody

Product Specifications

Background

SYT4 may be involved in Ca (2+) -dependent exocytosis of secretory vesicles through Ca (2+) and phospholipid binding to the C2 domain or may serve as Ca (2+) sensors in the process of vesicular trafficking and exocytosis.

NCBI Gene ID

6860

Swiss Prot

Q9H2B2

Accession Number

Q9H2B2

Host

Rabbit

Reactivity

Human

Immunogen

This SYT4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-85 amino acids from the N-terminal region of human SYT4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

48 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SYT4

NCBI Official Name

Synaptotagmin-4

NCBI Organism

Homo sapiens

Background Reference 01

Need, A.C., et al. Eur. J. Hum. Genet. 17 (7) :946-957 (2009)

Background Reference 02

Sonuga-Barke, E.J., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 147B (8), 1359-1368 (2008) :

Background Reference 03

Ferguson, G.D., et al. J. Biol. Chem. 275 (47) :36920-36926 (2000)

Background Reference 04

Mizutani, A., et al. J. Biol. Chem. 275 (13) :9823-9831 (2000)

Other Product Names

Synaptotagmin-4, Synaptotagmin IV, SytIV, SYT4, KIAA1342

Tested Applications

Protein ID

18202937

Physical Properties

Liquid

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