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TNPO1 Antibody

Product Specifications

Background

TNPO1 comprises the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins.

NCBI Gene ID

3842

Swiss Prot

Q92973

Accession Number

Q92973

Host

Rabbit

Reactivity

Human

Immunogen

This TNPO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 47-74 amino acids from the N-terminal region of human TNPO1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

102 kDa

Fragment

Rabbit Ig

Symbol

TNPO1

NCBI Official Name

Transportin-1

NCBI Organism

Homo sapiens

Background Reference 01

Fineberg, K., et al., Biochemistry 42 (9) :2625-2633 (2003) .

Background Reference 02

Nelson, L.M., et al., Virology 306 (1) :162-169 (2003) .

Background Reference 03

Le Roux, L.G., et al., J. Virol. 77 (4) :2330-2337 (2003) .

Background Reference 04

Limon, A., et al., J. Virol. 76 (21) :10598-10607 (2002) .

Other Product Names

Transportin-1, Importin beta-2, Karyopherin beta-2, M9 region interaction protein, MIP, TNPO1, KPNB2, MIP1, TRN

Tested Applications

WB, IHC-P, Flow

Protein ID

259016171

Physical Properties

Liquid

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