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HMOX2 Antibody

Product Specifications

Background

Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. Alternative splice variants encoding the same protein have been identified at this locus.

NCBI Gene ID

3163

Swiss Prot

P30519

Accession Number

P30519

Host

Rabbit

Reactivity

Human

Immunogen

This HMOX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-52 amino acids from the N-terminal region of human HMOX2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Obesity

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Monkey, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

36 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

HMOX2

NCBI Official Name

Heme oxygenase 2

NCBI Organism

Homo sapiens

Background Reference 01

Abdel Aziz, M.T., et al. Andrologia 42 (4) :236-241 (2010)

Background Reference 02

Wang, Y., et al. J. Hum. Genet. 55 (8) :490-494 (2010)

Background Reference 03

He, J.Z., et al. J. Biol. Chem. 285 (13) :9452-9461 (2010)

Background Reference 04

Zhong, J.L., et al. Free Radic. Biol. Med. 48 (2) :196-206 (2010)

Other Product Names

Heme oxygenase 2, HO-2, HMOX2, HO2

Tested Applications

WB

Protein ID

1170328

Physical Properties

Liquid

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