HMOX2 Antibody
Product Specifications
Background
Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. Alternative splice variants encoding the same protein have been identified at this locus.
NCBI Gene ID
3163
Swiss Prot
P30519
Accession Number
P30519
Host
Rabbit
Reactivity
Human
Immunogen
This HMOX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-52 amino acids from the N-terminal region of human HMOX2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Obesity
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Monkey, Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
36 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
HMOX2
NCBI Official Name
Heme oxygenase 2
NCBI Organism
Homo sapiens
Background Reference 01
Abdel Aziz, M.T., et al. Andrologia 42 (4) :236-241 (2010)
Background Reference 02
Wang, Y., et al. J. Hum. Genet. 55 (8) :490-494 (2010)
Background Reference 03
He, J.Z., et al. J. Biol. Chem. 285 (13) :9452-9461 (2010)
Background Reference 04
Zhong, J.L., et al. Free Radic. Biol. Med. 48 (2) :196-206 (2010)
Other Product Names
Heme oxygenase 2, HO-2, HMOX2, HO2
Tested Applications
WB
Protein ID
1170328
Physical Properties
Liquid
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