PPP2R5D Antibody

Product Specifications

Background

The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a delta isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified.

NCBI Gene ID

5528

Swiss Prot

Q14738

Accession Number

Q14738

Host

Rabbit

Reactivity

Human

Immunogen

This PPP2R5D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-91 amino acids from the N-terminal region of human PPP2R5D.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rb

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

70 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PPP2R5D

NCBI Official Name

Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

NCBI Organism

Homo sapiens

Background Reference 01

Yu, U.Y., et al. BMB Rep 43 (4) :263-267 (2010)

Background Reference 02

Reece, K.M., et al. Biochem. Biophys. Res. Commun. 386 (4) :582-587 (2009)

Background Reference 03

Forester, C.M., et al. Proc. Natl. Acad. Sci. U.S.A. 104 (50) :19867-19872 (2007)

Background Reference 04

Sablina, A.A., et al. Cell 129 (5) :969-982 (2007)

Other Product Names

Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform, PP2A B subunit isoform B'-delta, PP2A B subunit isoform B56-delta, PP2A B subunit isoform PR61-delta, PP2A B subunit isoform R5-delta, PPP2R5D