SIRPB1 Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

NCBI Gene ID

10326

Swiss Prot

O00241

Accession Number

O00241

Host

Rabbit

Reactivity

Human

Immunogen

This SIRPB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 107-134 amino acids from the Central region of human SIRPB1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

43 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SIRPB1

NCBI Official Name

Signal-regulatory protein beta-1

NCBI Organism

Homo sapiens

Background Reference 01

Gaikwad, S., et al. Am. J. Pathol. 175 (6) :2528-2539 (2009)

Background Reference 02

Martins-de-Souza, D., et al. Eur Arch Psychiatry Clin Neurosci 259 (3) :151-163 (2009)

Background Reference 03

Martins-de-Souza, D., et al.Neural Transm 116 (3) :275-289 (2009)

Background Reference 04

Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

Other Product Names

Signal-regulatory protein beta-1, SIRP-beta-1, CD172 antigen-like family member B, CD172b, SIRPB1

Tested Applications

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MC219255 10 µg

Fam83d (NM_027975) Mouse Untagged Clone

Ask

View Details

ABC-X3402 1 Vial

Xpress™ Human VLDLR Over-expressing Stable Cell Line

Ask

View Details

KV0014-01 3 mL

Calretinin Mouse mAb IHC Kit

Ask

View Details

KV0014-02 6 mL

Calretinin Mouse mAb IHC Kit

Ask

View Details

KV0014-03 10 mL

Calretinin Mouse mAb IHC Kit

Ask

View Details

MBS1067078-01 0.02 mg (E-Coli)

Recombinant Bombyx mori Tubulin beta chain

Ask

View Details