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SEPT12 Antibody

Product Specifications

Background

Septins, such as SEPT12, are conserved GTP-binding proteins that function as dynamic, regulatable scaffolds for the recruitment of other proteins. They are involved in membrane dynamics, vesicle trafficking, apoptosis, and cytoskeleton remodeling, as well as infection, neurodegeneration, and neoplasia (Hall et al., 2005 [PubMed 15915442]) .

NCBI Gene ID

124404

Swiss Prot

Q8IYM1

Accession Number

Q8IYM1

Host

Rabbit

Reactivity

Human

Immunogen

This SEPT12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-244 amino acids from the Central region of human SEPT12.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

41 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SEPT12

NCBI Official Name

Septin-12

NCBI Organism

Homo sapiens

Background Reference 01

Lin, Y.H., et al. Am. J. Pathol. 174 (5) :1857-1868 (2009)

Background Reference 02

Ding, X., et al. Mol. Cells 25 (3) :385-389 (2008)

Background Reference 03

Ding, X., et al. J. Biochem. Mol. Biol. 40 (6) :973-978 (2007)

Background Reference 04

Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

Other Product Names

Septin-12, SEPT12

Tested Applications

WB

Protein ID

74750767

Physical Properties

Liquid

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