SEPT12 Antibody
Product Specifications
Background
Septins, such as SEPT12, are conserved GTP-binding proteins that function as dynamic, regulatable scaffolds for the recruitment of other proteins. They are involved in membrane dynamics, vesicle trafficking, apoptosis, and cytoskeleton remodeling, as well as infection, neurodegeneration, and neoplasia (Hall et al., 2005 [PubMed 15915442]) .
NCBI Gene ID
124404
Swiss Prot
Q8IYM1
Accession Number
Q8IYM1
Host
Rabbit
Reactivity
Human
Immunogen
This SEPT12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-244 amino acids from the Central region of human SEPT12.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
41 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SEPT12
NCBI Official Name
Septin-12
NCBI Organism
Homo sapiens
Background Reference 01
Lin, Y.H., et al. Am. J. Pathol. 174 (5) :1857-1868 (2009)
Background Reference 02
Ding, X., et al. Mol. Cells 25 (3) :385-389 (2008)
Background Reference 03
Ding, X., et al. J. Biochem. Mol. Biol. 40 (6) :973-978 (2007)
Background Reference 04
Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)
Other Product Names
Septin-12, SEPT12
Tested Applications
WB
Protein ID
74750767
Physical Properties
Liquid
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