MRPL19 Antibody

Product Specifications

Background

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq].

NCBI Gene ID

9801

Swiss Prot

P49406

Accession Number

P49406

Host

Rabbit

Reactivity

Human

Immunogen

This MRPL19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-76 amino acids from the N-terminal region of human MRPL19.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

34 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

MRPL19

NCBI Official Name

39S ribosomal protein L19, mitochondrial

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 02

Anthoni, H., et al. Hum. Mol. Genet. 16 (6) :667-677 (2007)

Background Reference 03

Hillier, L.W., et al. Nature 434 (7034) :724-731 (2005)

Background Reference 04

Zhang, Z., et al. Genomics 81 (5) :468-480 (2003)

Other Product Names

39S ribosomal protein L19, mitochondrial, L19mt, MRP-L19, 39S ribosomal protein L15, mitochondrial, L15mt, MRP-L15, MRPL19, KIAA0104, MRPL15

Tested Applications

Protein ID

92090636

Physical Properties

Liquid

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