AQP3 Antibody

Product Specifications

Background

Aquaporin 3 is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0) . Aquaporin 3 is localized at the basal lateral membranes of collecting duct cells in the kidney. In addition to its water channel function, aquaporin 3 has been found to facilitate the transport of nonionic small solutes such as urea and glycerol, but to a smaller degree. It has been suggested that water channels can be functionally heterogeneous and possess water and solute permeation mechanisms.

NCBI Gene ID

360

Swiss Prot

Q92482

Accession Number

Q92482

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This AQP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 163-191 amino acids from the Central region of human AQP3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

32 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

AQP3

NCBI Official Name

Aquaporin-3

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 02

Kim, N.H., et al. J. Invest. Dermatol. 130 (9) :2231-2239 (2010)

Background Reference 03

Ji, C., et al. Int. J. Mol. Med. 26 (2) :257-263 (2010)

Background Reference 04

Melis, M., et al. Dis. Colon Rectum 53 (6) :936-943 (2010)

Other Product Names

Aquaporin-3, AQP-3, Aquaglyceroporin-3, AQP3

Tested Applications

Protein ID

2497938

Physical Properties

Liquid

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