ITGB1 Antibody
Product Specifications
Background
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.
NCBI Gene ID
3688
Swiss Prot
P05556
Accession Number
P05556
Host
Rabbit
Reactivity
Human
Immunogen
This ITGB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 759-785 amino acids from the C-terminal region of human ITGB1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Immunology, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat, Pig, Chicken, Xenopus, Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
88 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ITGB1
NCBI Official Name
Integrin beta-1
NCBI Organism
Homo sapiens
Background Reference 01
Martchenko, M., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (35) :15583-15588 (2010) Caicedo-Carvajal, C.E., et al. PLoS ONE (7), E11830 (2010) Rikova, K., et al. Cell 131 (6) :1190-1203 (2007) Seales, E.C., et al. J. Biol. Chem. 280 (45) :37610-37615 (2005) Armulik, A. Front. Biosci. 7, D219-D227 (2002) :
Other Product Names
Integrin beta-1, Fibronectin receptor subunit beta, Glycoprotein IIa, GPIIA, VLA-4 subunit beta, CD29, ITGB1, FNRB, MDF2, MSK12
Tested Applications
WB
Protein ID
218563324
Physical Properties
Liquid
Frequently Asked Questions
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