ITGB1 Antibody

Product Specifications

Background

Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.

NCBI Gene ID

3688

Swiss Prot

P05556

Accession Number

P05556

Host

Rabbit

Reactivity

Human

Immunogen

This ITGB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 759-785 amino acids from the C-terminal region of human ITGB1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Immunology, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat, Pig, Chicken, Xenopus, Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

88 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ITGB1

NCBI Official Name

Integrin beta-1

NCBI Organism

Homo sapiens

Background Reference 01

Martchenko, M., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (35) :15583-15588 (2010) Caicedo-Carvajal, C.E., et al. PLoS ONE (7), E11830 (2010) Rikova, K., et al. Cell 131 (6) :1190-1203 (2007) Seales, E.C., et al. J. Biol. Chem. 280 (45) :37610-37615 (2005) Armulik, A. Front. Biosci. 7, D219-D227 (2002) :